17-Hydroxy-19-norpregn-4-ene-3,20-dione(CAS: 2137-18-0)

17-Hydroxy-19-norpregn-4-ene-3,20-dione (CAS: 2137-18-0) is a crystalline compound with a molecular weight of approximately 356.42 g/mol. It has a melting point of 160-162°C and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is stable but can react with strong acids or bases. It is often used in steroid chemistry and biopharmaceuticals.

17-Hydroxy-19-norpregn-4-ene-3,20-dione is typically synthesized through the reduction of 17-oxo-19-norpregn-4-ene-3,20-dione using a hydrogenation catalyst like palladium on carbon. The reaction is typically conducted in an organic solvent such as ethanol under hydrogen pressure. The yield is generally good, and the process is highly selective. The product is then purified by recrystallization.

17-Hydroxy-19-norpregn-4-ene-3,20-dione (CAS: 2137-18-0) is primarily used in the pharmaceutical industry for the synthesis of steroid hormones and other biopharmaceuticals. It is also utilized in the research of steroid-related compounds in academia and in the development of new drugs.

When handling 17-Hydroxy-19-norpregn-4-ene-3,20-dione (CAS: 2137-18-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spillage, use a fume hood and follow standard safety procedures. Always consult a Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.