1-[1'-(2-Methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one(CAS: 634616-95-8)

1-[1'-(2-Methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one is a crystalline compound with a molecular weight of approximately 468.5 g/mol. It has a low water solubility and is moderately soluble in organic solvents like methanol and DMSO. The compound is known for its chemical stability and moderate reactivity under normal conditions.

1-[1'-(2-Methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one can be synthesized via a multi-step process involving condensation reactions and amidation. Commonly, this involves the use of 2-methylbenzylamine and 1,4'-bipiperidine followed by amidation with a benzimidazolone derivative. The yield is typically moderate to good, and the reaction is performed under mild conditions.

1-[1'-(2-Methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one is used in the pharmaceutical industry for its potential anti-inflammatory and analgesic properties. It is also explored in the polymer industry for its ability to enhance material properties and in sensor technology for its chemical reactivity.

When handling 1-[1'-(2-Methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, handle it according to the material safety data sheet (MSDS) recommendations. Proper disposal and storage should follow standard laboratory safety protocols.