(+)-1,4-Di-O-benzyl-D-threitol(CAS: 91604-41-0)

The (R)-enantiomer of (+)-1,4-Di-O-benzyl-D-threitol (CAS: 91604-41-0) is a white crystalline solid with a molecular weight of approximately 322.34 g/mol. It is poorly soluble in water but soluble in common organic solvents like chloroform and ethanol. This compound has a moderate reactivity towards nucleophiles and electrophiles. It can be used in organic synthesis as a chiral building block.

The (R)-enantiomer of (+)-1,4-Di-O-benzyl-D-threitol (CAS: 91604-41-0) can be synthesized via a stereoselective reaction of D-threitol with benzyl chloride in the presence of a Lewis acid catalyst. The reaction yields a high enantiomeric excess, typically greater than 99%, with good yield. This method is commonly used in the preparation of optically active compounds for pharmaceutical and biochemical applications.

The (R)-enantiomer of (+)-1,4-Di-O-benzyl-D-threitol (CAS: 91604-41-0) is widely used in the pharmaceutical industry for the synthesis of chiral drugs. It is also utilized in the polymer industry for the development of advanced materials and in the sensor industry for the construction of biosensors. Additionally, it has applications in the semiconductor industry as a chiral ligand in metal-organic chemical vapor deposition (MOCVD) processes.

When handling (+)-1,4-Di-O-benzyl-D-threitol (CAS: 91604-41-0), it is essential to use appropriate personal protective equipment (PPE), such as gloves, safety goggles, and a lab coat. Work should be performed in a well-ventilated hood to minimize inhalation risks. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of in a hazardous waste container. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.