4-Acetyl-1,3-benzoxazol-2(3H)-one(CAS: 70735-79-4)

4-Acetyl-1,3-benzoxazol-2(3H)-one is a crystalline solid with a molecular weight of approximately 211.23 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but can be susceptible to oxidation in air. It is known for its reactivity towards nucleophiles and can undergo various transformations in chemical reactions.

4-Acetyl-1,3-benzoxazol-2(3H)-one can be synthesized via condensation reactions. One common method involves the reaction of benzoxazole with acetic anhydride in the presence of a suitable catalyst, such as pyridine. The reaction yields a mixture of products, but with good selectivity towards the desired compound. The yield is typically around 70-80%.

4-Acetyl-1,3-benzoxazol-2(3H)-one finds applications in various industries. It is used in the pharmaceutical sector as an intermediate for drug synthesis. In the polymer industry, it can serve as a stabilizer or additive. Additionally, it is employed in the production of sensors and semiconductors due to its unique electronic properties.

When handling 4-Acetyl-1,3-benzoxazol-2(3H)-one, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.