2-Hydroxy-L-tryptophan(CAS: 21704-80-3)

2-Hydroxy-L-tryptophan is a white to off-white powder, with a crystalline form. Its molecular weight is approximately 194.23 g/mol. It is slightly soluble in water and ethanol, and insoluble in organic solvents. This compound is not highly reactive under normal conditions but can undergo hydrolysis in basic media. It is stable under acidic conditions and should be stored in a cool, dry place away from direct sunlight.

2-Hydroxy-L-tryptophan can be synthesized by the reduction of L-tryptophylglycine, using hydrogen and a catalyst such as palladium on carbon. The reaction is performed under mild conditions and yields a product with high purity and selectivity. The process typically involves a one-step reaction, providing a yield of around 70-80% under optimal conditions.

2-Hydroxy-L-tryptophan is primarily used in the pharmaceutical industry for the production of certain drugs that require L-tryptophan derivatives. It is also used in the food industry as a flavor enhancer and in research laboratories for studying the biochemistry of tryptophan and its derivatives. Additionally, it has potential applications in the polymer and semiconductor industries.

When handling 2-Hydroxy-L-tryptophan, it is recommended to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up with care, using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information and specific handling guidelines.