(2S)-2-amino-3-(carbamoylamino)propanoic acid(CAS: 1483-07-4)

(2S)-2-amino-3-(carbamoylamino)propanoic acid is a crystalline solid with a molecular weight of approximately 198.19 g/mol. It is slightly soluble in water and has a pKa of about 7.5. The compound is reactive, particularly with bases, and can undergo hydrolysis and condensation reactions.

(2S)-2-amino-3-(carbamoylamino)propanoic acid can be synthesized via the condensation of 2-amino-3-carboxypropanoic acid with hydroxylamine. The reaction is catalyzed by a Lewis acid like boron trifluoride, and the yield is around 85%. Selectivity is high, and the product can be purified by recrystallization.

(2S)-2-amino-3-(carbamoylamino)propanoic acid finds applications in the pharmaceutical industry, particularly in the synthesis of certain antibiotics and immunosuppressive agents. It also has uses in the polymer and sensor industries for specific chemical sensing applications.

When handling (2S)-2-amino-3-(carbamoylamino)propanoic acid, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and lab coat. The compound should be stored in a cool, dry place away from heat sources. In case of a spill, use appropriate containment and dispose of the material according to the Safety Data Sheet (SDS).