(3S)-3-Hydroxydihydro-2(3H)-furanone(CAS: 52079-23-9)

(3S)-3-Hydroxydihydro-2(3H)-furanone is a colorless to light yellow liquid with a fruity odor. It has a molecular weight of approximately 128.14 g/mol and a boiling point of 225°C. This compound is soluble in ethanol and acetone but slightly soluble in water. It is known for its low reactivity under normal conditions, but it can undergo hydrolysis in the presence of acids or bases.

(3S)-3-Hydroxydihydro-2(3H)-furanone can be synthesized through a multi-step process involving the reduction of a furanone derivative followed by the hydroxylation of the double bond. Common catalysts include palladium on carbon. The yield is typically around 70-80%, and the method is known for its good selectivity towards the (3S) isomer.

(3S)-3-Hydroxydihydro-2(3H)-furanone is primarily used in the fragrance and flavor industry as a natural ingredient. It is also utilized in the pharmaceutical industry for its potential biological activities, and in the food industry as a flavor enhancer. Additionally, it can be applied in polymer synthesis and as a chemical intermediate in the production of other compounds.

When handling (3S)-3-Hydroxydihydro-2(3H)-furanone, it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coat. It should be stored in a cool, dry place, away from direct sunlight and heat sources. Spills should be cleaned up with care using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.