2,2-Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)acetonitrile(CAS: 1442644-14-5)

2,2-Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)acetonitrile has a crystalline form with a molecular weight of approximately 374.41 g/mol. It is slightly soluble in water but soluble in organic solvents like methanol and dichloromethane. The compound is chemically stable but may react with strong acids or bases. It is a potent ligand and exhibits good thermal stability.

2,2-Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)acetonitrile can be synthesized via a multi-step process involving the condensation of indolines and nitrile precursors. The reaction is typically catalyzed by palladium or a similar transition metal, with high selectivity and good yield. The process requires careful control of reaction conditions, including temperature and solvent choice.

2,2-Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)acetonitrile is primarily used in pharmaceuticals and as a ligand in catalysis. Its role as a ligand makes it valuable in the development of new materials and in the synthesis of complex organic molecules. It is also explored in the field of sensors and semiconductors for its unique chemical properties.

Proper handling of 2,2-Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)acetonitrile requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of spill, it is important to clean up using appropriate absorbents and dispose of the waste according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS).