5-(4-Chlorophenyl)-1H-pyrazole(CAS: 59843-58-2)

5-(4-Chlorophenyl)-1H-pyrazole is a crystalline solid with a molecular weight of approximately 211.02 g/mol. It has a melting point of 190-191°C and is slightly soluble in water. This compound shows moderate reactivity, particularly towards nucleophilic substitution reactions.

5-(4-Chlorophenyl)-1H-pyrazole is commonly synthesized via the reaction of 4-chlorobenzaldehyde with hydrazine hydrate followed by acetylation with acetic anhydride. This method provides good yields and is widely used in academic and industrial settings.

5-(4-Chlorophenyl)-1H-pyrazole is utilized in the pharmaceutical industry for the development of certain drugs. It also has applications in the production of certain polymers and as a precursor in the synthesis of organic electronic materials such as semiconductors and sensors.

When handling 5-(4-Chlorophenyl)-1H-pyrazole, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. In case of spillage, it is advised to use appropriate containment and disposal methods as outlined in the material safety data sheet (MSDS).