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5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE(CAS: 666848-11-9)
CAS Number
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Other Suppliers for 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE
Basic Information
Molecular Formula
C15H26IN3O4Si
Molecular Weight
467.38 g/mol
Chemical Identifiers
SMILES
O[C@@H](C[C@H](N1C(N=C(C(I)=C1)N)=O)O2)[C@H]2CO[Si](C)(C(C)(C)C)C
InChIKey
GKUIXIRTAVPIGD-QJPTWQEYSA-N
Database References
MDL Number
MFCD09264239
FAQ
The compound 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE is a crystalline solid with a molecular weight of approximately 425.2 g/mol. It has limited water solubility and is known for its reactivity due to the presence of the iodine substituent. The compound is stable under normal conditions but requires careful handling to avoid degradation.
5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE is typically synthesized via a multi-step process involving protection of the hydroxyl group, introduction of the iodine substituent, and deprotection. Common reagents include tert-butyldimethylsilyl chloride and iodine, with the use of anhydrous conditions and appropriate solvents like dichloromethane.
5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE is primarily used in pharmaceutical research, particularly in the development of nucleoside analogs for antiviral and anticancer therapies. It may also find applications in the synthesis of DNA and RNA analogs for sensor and semiconductor technologies.
When handling 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up immediately using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed safety information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
