1H-Pyrrole-3-carboxamide(CAS: 71580-36-4)

1H-Pyrrole-3-carboxamide (CAS: 71580-36-4) is a white solid with a molecular weight of 131.12 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and dichloromethane. The compound is known for its basicity and can undergo nucleophilic substitution and condensation reactions.

1H-Pyrrole-3-carboxamide (CAS: 71580-36-4) can be synthesized by reacting pyrrole-3-carboxylic acid with an amine in the presence of a base. Commonly, triethylamine is used as the base, and the reaction is performed in an organic solvent like dichloromethane or ethyl acetate.

1H-Pyrrole-3-carboxamide (CAS: 71580-36-4) is used in the pharmaceutical industry for the synthesis of drug intermediates, particularly in the development of anti-inflammatory and antihistaminic drugs. It also finds applications in the polymer industry as a stabilizer and in the semiconductor industry for doping materials.

When handling 1H-Pyrrole-3-carboxamide (CAS: 71580-36-4), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety instructions.