4-Oxo-3-piperidinecarbonitrile(CAS: 19166-75-7)

4-Oxo-3-piperidinecarbonitrile is a white crystalline solid with a molecular weight of approximately 175.15 g/mol. It is only slightly soluble in water but soluble in organic solvents such as dichloromethane and acetone. This compound is highly reactive and can undergo various reactions such as nucleophilic substitution and condensation.

4-Oxo-3-piperidinecarbonitrile can be synthesized by the condensation of 3-piperidinamidocarbonyl chloride with ethylene oxide followed by hydrolysis of the resulting amide. Other methods include the reaction of piperidine with acrylonitrile in the presence of a suitable catalyst such as a base.

4-Oxo-3-piperidinecarbonitrile is mainly used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the polymer industry as a monomer for the production of certain polymers. Additionally, it can be used in the preparation of sensors and as a precursor in semiconductor manufacturing.

When handling 4-Oxo-3-piperidinecarbonitrile, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and chemical-resistant clothing. Ensure the work is conducted in a well-ventilated area or a fume hood. Dispose of any spills or waste materials according to local regulations and refer to the Safety Data Sheet (SDS) for detailed information.