1-(9H-Fluoren-9-yl)-3,11-dioxo-2,7-dioxa-4,10-diazatetradecan-14-oic acid(CAS: 669073-62-5)

1-(9H-Fluoren-9-yl)-3,11-dioxo-2,7-dioxa-4,10-diazatetradecan-14-oic acid is a crystalline compound with a molecular weight of approximately 442.36 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and acetonitrile. Chemically, it is reactive towards nucleophiles, making it useful in various synthetic transformations. Its high reactivity towards electrophiles also makes it an interesting reagent in organic chemistry.

1-(9H-Fluoren-9-yl)-3,11-dioxo-2,7-dioxa-4,10-diazatetradecan-14-oic acid is synthesized via a multi-step process starting from fluorene. The key steps involve alkylation, oxidations, and amidation reactions. Commonly, this involves the use of potassium periodate for oxidation and chloroacetyl chloride for amidation. The overall yield is moderate, around 50-60%, and the purity can be achieved through recrystallization.

1-(9H-Fluoren-9-yl)-3,11-dioxo-2,7-dioxa-4,10-diazatetradecan-14-oic acid finds applications in pharmaceuticals, where it serves as a building block for complex molecules. It is also used in the synthesis of polymers for biomedical applications and in the development of sensors due to its unique chemical properties. Additionally, it has potential in the semiconductor industry for use in organic electronics.

When handling 1-(9H-Fluoren-9-yl)-3,11-dioxo-2,7-dioxa-4,10-diazatetradecan-14-oic acid, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.