6-Iodo-2-methyl-3-pyridinol(CAS: 848952-39-6)

6-Iodo-2-methyl-3-pyridinol is a crystalline solid with a molecular weight of approximately 233.05 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and heat.

6-Iodo-2-methyl-3-pyridinol is typically synthesized through a pyridine-based reaction involving the iodination of 2-methyl-3-pyridinol using iodine in the presence of a Lewis acid catalyst like aluminum trichloride. The reaction is carried out in a solvent like dichloromethane, with a yield of around 70-80% based on the starting material.

6-Iodo-2-methyl-3-pyridinol is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring iodine-based functional groups. It is also used in the sensor industry for the production of gas sensors, and in the semiconductor industry for the development of organic electronics materials.

When handling 6-Iodo-2-methyl-3-pyridinol, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood, and spill clean-up should be done following standard procedures. Keep the compound away from heat sources and ensure proper storage in a cool, dry place. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.