5-Bromo-1-methyl-1H-pyrazol-3-amine(CAS: 89088-55-1)

5-Bromo-1-methyl-1H-pyrazol-3-amine (CAS: 89088-55-1) appears as a white or off-white solid with a molecular weight of approximately 215.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. This compound is known for its good stability under normal conditions but can react with strong oxidizing agents. It is often used in organic synthesis and pharmaceutical applications.

5-Bromo-1-methyl-1H-pyrazol-3-amine can be synthesized through a multi-step process involving bromination of 1-methyl-1H-pyrazol-3-amine. This typically involves the use of bromine in the presence of a base like sodium hydroxide. The reaction is carried out in an aprotic solvent such as acetonitrile. The yield is usually between 60-80%, and the reaction is highly selective for the bromination of the amine group.

5-Bromo-1-methyl-1H-pyrazol-3-amine (CAS: 89088-55-1) is primarily used in the pharmaceutical and fine chemical industries. It serves as a precursor in the synthesis of certain drugs and is also used in the development of organic dyes and sensors. Due to its versatility, it finds applications in the production of materials for semiconductors and polymers as well.

When handling 5-Bromo-1-methyl-1H-pyrazol-3-amine (CAS: 89088-55-1), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. It is important to use a fume hood during synthesis and manipulation to avoid inhalation of fumes. In case of a spill, use absorbent material and notify the safety officer immediately. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.