2-Bromo-1-(3,4-difluorophenyl)ethanone(CAS: 40706-98-7)

2-Bromo-1-(3,4-difluorophenyl)ethanone (CAS: 40706-98-7) is a white or off-white crystalline solid with a molecular weight of approximately 260.04 g/mol. It has a low solubility in water but is soluble in organic solvents like dichloromethane and acetonitrile. It is moderately reactive, especially towards nucleophiles and bases. It can undergo bromination and conjugate addition reactions.

2-Bromo-1-(3,4-difluorophenyl)ethanone (CAS: 40706-98-7) is typically synthesized via a bromination reaction of 1-(3,4-difluorophenyl)ethanone with bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction involves electrophilic aromatic substitution followed by bromination to yield the desired product with high selectivity and yield.

2-Bromo-1-(3,4-difluorophenyl)ethanone (CAS: 40706-98-7) is used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in polymer synthesis, particularly in the development of novel functional polymers. Additionally, it is utilized in sensor technologies and semiconductors for its unique chemical properties.

When handling 2-Bromo-1-(3,4-difluorophenyl)ethanone (CAS: 40706-98-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using appropriate chemical spill cleanup materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.