Pregn-4-ene-3,6,20-trione(CAS: 2243-08-5)

Pregn-4-ene-3,6,20-trione (CAS: 2243-08-5) is a cyclic ketone with a molecular weight of approximately 282.35 g/mol. It is a white crystalline solid with a melting point around 133-135°C and a boiling point above 300°C. This compound has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophilic attacks and hydrogenation reactions.

Pregn-4-ene-3,6,20-trione (CAS: 2243-08-5) can be synthesized via a variety of methods, including Wittig olefination followed by oxidation. Common synthetic routes involve the use of phosphonium ylides and oxidants like potassium permanganate or Dess-Martin periodinane. The reaction typically requires mild conditions and high selectivity, with good to excellent yields.

Pregn-4-ene-3,6,20-trione (CAS: 2243-08-5) is primarily used in the pharmaceutical industry for the synthesis of progestogens, which are important hormones in birth control and other medical applications. It also finds use in polymer chemistry for the development of novel materials with specific properties. Additionally, this compound can be used in the production of chemical sensors and as a precursor in semiconductor manufacturing processes.

When handling Pregn-4-ene-3,6,20-trione (CAS: 2243-08-5), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. This compound should be stored in a cool, well-ventilated area away from sources of heat and ignition. Handling should be done in a fume hood to minimize inhalation risks. In the event of a spill, it should be immediately cleaned up with appropriate absorbent materials and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information and guidelines.