(3R)-3-(2,3-Dichlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid(CAS: 500788-91-0)

(3R)-3-(2,3-Dichlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 500788-91-0) is a white to off-white crystalline solid. It has a molecular weight of approximately 318.04 g/mol and is slightly soluble in water. This compound is relatively stable but can react with strong bases or reducing agents. It exhibits a pKa around 4.2, indicating it is a weak acid.

(3R)-3-(2,3-Dichlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 500788-91-0) is synthesized via the condensation of a 2,3-dichlorophenyl compound with 2-methyl-2-propanol followed by acylation. The reaction is performed in the presence of a base such as sodium hydride or potassium tert-butoxide, with a yield of up to 85%. The reaction is conducted under an inert atmosphere to prevent oxidation.

(3R)-3-(2,3-Dichlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 500788-91-0) has applications in pharmaceuticals, where it serves as an intermediate in the synthesis of drug molecules. It is also used in the development of sensors and as a reagent in organic synthesis. Its use in polymers and semiconductors is currently under exploration due to its unique physicochemical properties.

When handling (3R)-3-(2,3-Dichlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 500788-91-0), it is important to wear personal protective equipment (PPE) such as gloves, goggles, and lab coat. It should be stored in a cool, dry place away from incompatible materials. Fume hoods should be used during handling to minimize exposure. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always consult the Material Safety Data Sheet (MSDS) for detailed handling and disposal information.