1H-Pyrazol-1-ylacetaldehyde(CAS: 99310-58-4)

1H-Pyrazol-1-ylacetaldehyde (CAS: 99310-58-4) is a colorless liquid with a molecular weight of approximately 112.12 g/mol. It has a melting point of -84°C, boiling point of 131°C, and a density of 0.98 g/cm³. This compound is poorly soluble in water but soluble in organic solvents like ethanol and acetone. It is known for its reactivity, particularly in nucleophilic substitution and addition reactions.

1H-Pyrazol-1-ylacetaldehyde (CAS: 99310-58-4) can be synthesized via various methods, including the condensation of pyrazole with acetaldehyde, or by the catalytic hydrogenation of pyrazine-2-carbaldehyde. Common catalysts include palladium on carbon and other transition metal complexes. The yield and selectivity are typically high, and the product can be purified by column chromatography or distillation.

1H-Pyrazol-1-ylacetaldehyde (CAS: 99310-58-4) is primarily used in the pharmaceutical industry for the synthesis of certain drugs, and in the semiconductor industry for the production of organic electronic materials. It is also utilized in the development of new materials for sensors and as a precursor in polymer synthesis.

When handling 1H-Pyrazol-1-ylacetaldehyde (CAS: 99310-58-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed safety information.