4-Pentenylboronic acid(CAS: 886747-03-1)

4-Pentenylboronic acid is a white crystalline solid with a molecular weight of approximately 170.23 g/mol. It has a high solubility in organic solvents such as ethanol and acetone, but is poorly soluble in water. Chemically, it shows typical reactivity of organoboronic acids, such as participation in Suzuki coupling reactions with aryl halides. It is stable under standard storage conditions but should be protected from moisture and air.

4-Pentenylboronic acid is typically synthesized through the reaction of 4-pentenylboronic ester with a base such as sodium hydroxide, followed by acidification to protonate the boronate ester. Catalysts like Pd(0) complexes can be used to improve the yield and selectivity in cross-coupling reactions. The overall process requires careful control of pH and temperature to achieve high purity.

4-Pentenylboronic acid is primarily used in the pharmaceutical and polymer industries. It is a key intermediate in the synthesis of boronic acid derivatives that are used in drug discovery and development. In the polymer industry, it serves as a functional monomer for the development of new materials with specific properties. Additionally, it has applications in sensor and semiconductor technology due to its reactivity.

When handling 4-Pentenylboronic acid, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from moisture and air to prevent degradation. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) for the compound.