3-Bromo-5-chloro-2-methylaniline(CAS: 1166756-72-4)

3-Bromo-5-chloro-2-methylaniline (CAS: 1166756-72-4) is a crystalline solid with a molecular weight of approximately 216.02 g/mol. It has a solubility of 0.01 g/L in water. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is insoluble in water but soluble in organic solvents like methanol and ethanol.

3-Bromo-5-chloro-2-methylaniline (CAS: 1166756-72-4) is typically synthesized by the sequential bromination and chlorination of 2-methylaniline, followed by nitration and reduction steps. Common reagents include bromine, chlorine, and nitric acid. The synthesis requires careful control of reaction conditions and specific catalysts to achieve high selectivity and yield.

3-Bromo-5-chloro-2-methylaniline (CAS: 1166756-72-4) is primarily used in the pharmaceutical industry for the synthesis of certain medicinals. It is also utilized in the production of dyes and intermediates for the polymer industry. Additionally, it can be applied in the field of chemical sensors and as a precursor in the semiconductor industry.

When handling 3-Bromo-5-chloro-2-methylaniline (CAS: 1166756-72-4), safety measures include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to prevent inhalation of vapors. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for specific guidelines and emergency procedures.