3-(2-Cyano-2-propanyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydro-6-quinazolinyl)amino]phenyl}benzamide(CAS: 878739-06-1)

3-(2-Cyano-2-propanyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydro-6-quinazolinyl)amino]phenyl}benzamide is a crystalline solid with a molecular weight of approximately 569.4 g/mol. It has a low solubility in water but is soluble in common organic solvents like DMSO and acetonitrile. The compound is moderately reactive towards nucleophiles and can undergo substitution reactions under appropriate conditions. It is stable under neutral and acidic conditions but decomposes under basic conditions.

3-(2-Cyano-2-propanyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydro-6-quinazolinyl)amino]phenyl}benzamide is synthesized through multi-step reactions involving the condensation of anhydride with a substituted aromatic amine, followed by coupling with a quinazolinone derivative. The reaction is typically conducted under an inert atmosphere, and the yield can be improved by using anhydrous solvents and appropriate catalysts. High selectivity and yield are achieved by optimizing reaction conditions.

3-(2-Cyano-2-propanyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydro-6-quinazolinyl)amino]phenyl}benzamide is primarily used in the pharmaceutical industry for the development of new drugs. It is also explored for its potential applications in the sensing technology and semiconductor industries due to its unique chemical properties.

When handling 3-(2-Cyano-2-propanyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydro-6-quinazolinyl)amino]phenyl}benzamide, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risk. Spills should be immediately addressed by sweeping or vacuuming, and the area should be cleaned with a suitable solvent. Always refer to the Safety Data Sheet (SDS) for specific handling and storage instructions.