(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol(CAS: 882881-15-4)

(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4) is a crystalline solid with a molecular weight of approximately 213.2 g/mol. It has limited water solubility but is more soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly towards nucleophilic substitution reactions. It exhibits good stability in neutral and basic media but is susceptible to degradation under acidic conditions.

(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4) can be synthesized through a multi-step process starting from pyrrole and 2-chloro-3-pyridine methanol. Common methods involve the condensation of pyrrole with 2-chloro-3-pyridine methanol, followed by reduction of the chloride group to achieve the methanol product. The synthesis typically uses palladium catalysts and is carried out in a solvent such as acetonitrile, with high selectivity and yield.

(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4) is primarily used in the pharmaceutical and polymer industries. It serves as a precursor in drug synthesis for designing new pharmaceutical compounds and as a functional group in polymer synthesis for developing advanced materials. Additionally, it has potential applications in sensor technology and semiconductor manufacturing, although these uses are more niche.

When handling (1H-Pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS: 882881-15-4), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. If spills occur, they should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.