6-FAM SE(CAS: 92557-81-8)

6-FAM SE (CAS: 92557-81-8) is a fluorescent dye with a molecular weight of approximately 411.4 g/mol. It has a melting point of around 210°C and is soluble in organic solvents like DMSO and ethanol. It exhibits high fluorescence efficiency and is often used in biochemistry and molecular biology. Chemically, it is reactive towards nucleophiles and can be used in various labeling applications.

6-FAM SE (CAS: 92557-81-8) is synthesized via a multi-step process starting with the coupling of 6-fluorofluorescein to a suitable amino compound. The synthesis involves cross-coupling reactions and typically uses catalysts like Pd(II) complexes. The product is isolated and purified via column chromatography, yielding a fluorescent dye with high purity.

6-FAM SE (CAS: 92557-81-8) is widely used in the pharmaceutical, biotechnology, and research industries. It is particularly important in molecular biology, where it serves as a labeling agent for nucleic acids, proteins, and other biomolecules. Its applications include fluorescence microscopy, flow cytometry, and DNA sequencing.

When handling 6-FAM SE (CAS: 92557-81-8), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately, and proper waste disposal procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.