6-bromo-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde(CAS: 1190312-27-6)

6-Bromo-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS: 1190312-27-6) is a crystalline solid with a molecular weight of approximately 275.04 g/mol. It has limited water solubility and is soluble in common organic solvents such as DMSO and acetonitrile. The compound is known for its reactivity, particularly towards nucleophiles, and is used in various chemical transformations due to its electron-withdrawing bromine substituent.

6-Bromo-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS: 1190312-27-6) can be synthesized via bromination of 1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde using N-bromosuccinimide (NBS) in the presence of a suitable base such as triethylamine. The reaction involves electrophilic aromatic substitution, leading to a high yield and good selectivity towards the brominated product.

6-Bromo-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS: 1190312-27-6) is primarily used in pharmaceuticals and chemical research for its reactivity and potential as a precursor in the synthesis of bioactive compounds. It also finds applications in materials science, particularly in the development of sensors and electronic devices.

When handling 6-bromo-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS: 1190312-27-6), it is crucial to use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid exposure to vapors. In case of a spill, immediately clean up the area using appropriate spill cleanup kits and ensure the area is well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.