4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline(CAS: 166096-16-8)

4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline (CAS: 166096-16-8) is a crystalline solid with a molecular weight of approximately 224.61 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetone. The compound is known for its reactivity, particularly towards nucleophilic substitution and electrophilic aromatic substitution reactions.

4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline (CAS: 166096-16-8) is typically synthesized through a multi-step process involving the coupling of 4-chloroaniline with 2-imidazolmethanol in the presence of a catalyst such as sodium hydride. The yield is usually high, and the reaction is selective, making it a reliable method for preparing this compound.

4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline (CAS: 166096-16-8) finds application in pharmaceuticals, where it serves as a precursor for the synthesis of certain antiviral and antifungal agents. It is also used in the production of organic semiconductors and sensors due to its unique chemical properties.

When handling 4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline (CAS: 166096-16-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up promptly using appropriate absorbents, and the Material Safety Data Sheet (MSDS) should be consulted for specific safety guidelines.