4-Bromo-1,8-naphthyridine(CAS: 54569-28-7)

4-Bromo-1,8-naphthyridine (CAS: 54569-28-7) is a crystalline solid with a molecular weight of approximately 245.03 g/mol. It has a melting point of 231-232°C and is slightly soluble in water. The compound shows good solubility in organic solvents like acetonitrile and dimethylformamide. It is known for its reactivity, particularly with nucleophiles, and displays significant electron-donating properties.

4-Bromo-1,8-naphthyridine (CAS: 54569-28-7) is commonly synthesized via the bromination of 1,8-naphthyridine with N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction provides good yields and high selectivity, making it a feasible method for large-scale production.

4-Bromo-1,8-naphthyridine (CAS: 54569-28-7) is primarily used in the pharmaceutical and chemical industries. It serves as an intermediate in the synthesis of various organic compounds and is also used in the development of sensors and other specialized applications due to its unique chemical properties.

When handling 4-Bromo-1,8-naphthyridine (CAS: 54569-28-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately and handled according to the Material Safety Data Sheet (SDS).