2-methoxy-3,4-dihydro-2H-pyran(CAS: 4454-05-1)

2-Methoxy-3,4-dihydro-2H-pyran (CAS: 4454-05-1) is a colorless to slightly yellow liquid with a molecular weight of approximately 130.17 g/mol and a density of 1.04 g/cm³. It has a low melting point of -16°C and a boiling point of 130°C. Soluble in water and organic solvents. It is relatively stable under normal conditions but may undergo ring-opening reactions with strong acids or bases.

2-Methoxy-3,4-dihydro-2H-pyran is typically synthesized through a Wittig reaction using methyl methoxy phosphonate and prop-2-enal, catalyzed by a Lewis acid like aluminum trichloride. The reaction is carried out in a suitable solvent like dichloromethane at room temperature, yielding a pure product with a high yield of up to 95%.

2-Methoxy-3,4-dihydro-2H-pyran (CAS: 4454-05-1) is used in the pharmaceutical industry for the synthesis of various drugs, in polymer chemistry as a monomer, and in the production of sensors and semiconductors due to its unique structural properties. It acts as a versatile building block in organic synthesis and finds applications in various other fields as well.

When handling 2-methoxy-3,4-dihydro-2H-pyran (CAS: 4454-05-1), use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhaling vapors. Store the compound in a tightly sealed container away from heat sources and incompatible materials. In case of a spill, use appropriate containment and follow the safety data sheet (SDS) for cleanup instructions.