4-Bromo-2,6-diisopropylaniline(CAS: 80058-84-0)

4-Bromo-2,6-diisopropylaniline is a white crystalline solid with a molecular weight of approximately 312.23 g/mol. It has low water solubility and is more soluble in organic solvents like acetone and toluene. The compound is moderately reactive and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from strong acids and bases.

4-Bromo-2,6-diisopropylaniline is typically synthesized by bromination of 2,6-diisopropylaniline using bromine in the presence of a catalyst such as iron(III) bromide. The reaction yields a mixture that can be purified through recrystallization. The process requires careful control of reaction conditions to achieve high selectivity and yield.

4-Bromo-2,6-diisopropylaniline is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring aromatic brominated intermediates. It is also used in the production of dyes and pigments, as well as in the synthesis of organic compounds for use in semiconductors and sensors.

When handling 4-Bromo-2,6-diisopropylaniline, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific disposal instructions. Storage should be in a cool, dry place away from heat sources and incompatible materials.