2-Bromo-5-(methylsulfanyl)pyrazine(CAS: 1049026-49-4)

2-Bromo-5-(methylsulfanyl)pyrazine (CAS: 1049026-49-4) is a crystalline solid with a molecular weight of approximately 230.03 g/mol. It is slightly soluble in water but more soluble in common organic solvents like ethanol and acetone. The compound is moderately reactive, particularly with nucleophiles. It shows good thermal stability but can decompose under strongly acidic or basic conditions.

2-Bromo-5-(methylsulfanyl)pyrazine (CAS: 1049026-49-4) can be synthesized via the reaction of 5-(methylthio)pyrazine with bromine in the presence of a suitable base like sodium hydroxide. The reaction is carried out in a polar aprotic solvent and typically yields a high selectivity for the brominated product.

2-Bromo-5-(methylsulfanyl)pyrazine (CAS: 1049026-49-4) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the production of sensors and semiconductors due to its unique chemical properties.

When handling 2-Bromo-5-(methylsulfanyl)pyrazine (CAS: 1049026-49-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The material should be handled in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials, and the area should be well ventilated. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.