1-(Hydroxymethyl)-6,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione(CAS: 76843-23-7)

1-(Hydroxymethyl)-6,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione is a yellow crystalline solid with a high melting point. It has a molecular weight of approximately 284.32 g/mol. This compound is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It is chemically stable but can react with strong acids to form its corresponding carboxylic acid derivative.

1-(Hydroxymethyl)-6,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione is usually synthesized via the Baeyer-Villiger oxidation of 6,6-dimethyl-1,2,3,4,5,6-hexahydro-1H-phenanthro[1,2-b]furan-10,11-dione. This process involves the use of peroxy acids like meta-chloroperoxybenzoic acid as the oxidant. The reaction yields the desired compound with high selectivity and good yield.

1-(Hydroxymethyl)-6,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione is utilized in the pharmaceutical industry for the production of certain medications. It has also been explored in the polymer industry for its potential as a monomer. Additionally, it shows promise in sensor technology due to its unique chemical structure and reactivity.

When handling 1-(Hydroxymethyl)-6,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbent materials and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.