N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}-4-quinazolinamine(CAS: 781613-23-8)

N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}-4-quinazolinamine is a solid with a crystalline form. Its molecular weight is approximately 606.02 g/mol. The compound has low solubility in water but is soluble in organic solvents like DMSO and acetonitrile. It is relatively stable under acidic and basic conditions but reacts with strong oxidizing agents. The compound is not flammable but requires careful handling due to its reactivity.

N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}-4-quinazolinamine is synthesized through multi-step organic synthesis, often involving protection of the amine group, coupling reactions, and subsequent deprotection. Highly selective catalysts such as palladium complexes are used to ensure high yield and purity. The exact synthesis route can vary based on the specific reagents and conditions chosen.

N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}-4-quinazolinamine is primarily used in the pharmaceutical industry for its potential therapeutic applications. It may also be employed in the development of new materials for sensors and semiconductors, given its special chemical structure and reactivity.

When handling N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}-4-quinazolinamine (CAS: 781613-23-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work in a fume hood to minimize inhalation risk. Avoid contact with skin and eyes. In case of spill, neutralize with a suitable base and dispose of according to local hazardous waste regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.