N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine(CAS: 158808-86-7)

N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine is a white crystalline solid with a molecular weight of approximately 380.53 g/mol. It has a pKa of around 7.5 and is poorly soluble in water but soluble in organic solvents like dichloromethane and ethanol. This compound exhibits moderate reactivity towards nucleophiles and can form stable adducts under mild conditions.

N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine is typically synthesized via a multi-step process involving condensation reactions and sulfonation. The key steps include coupling of butylamine with butyric anhydride to form the butylated piperidine, followed by coupling with tyrosine and subsequent sulfonation. Common catalysts include organometallic reagents and Lewis acids, yielding a product with high selectivity and good yield.

N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine is used in the pharmaceutical industry for the synthesis of complex organic compounds and as a building block for drug development. It is also applied in the polymer industry for modifying polymer properties and in the sensor industry for creating sensitive detection elements. Additionally, it has potential applications in semiconductor technology for specific chemical treatments.

When handling N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Operations should be carried out in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.