3-Phenyl-1H-pyrazol-5-amine(CAS: 1572-10-7)

3-Phenyl-1H-pyrazol-5-amine (CAS: 1572-10-7) is a crystalline solid with a molecular weight of approximately 161.22 g/mol. It has a solubility of 0.7 g/L in water and is relatively stable in air. This compound is used in various applications due to its chemical reactivity, particularly in the formation of coordination complexes and as a ligand in transition metal complexes.

3-Phenyl-1H-pyrazol-5-amine can be synthesized via the condensation of 5-amino-1H-pyrazole with phenyl isocyanate in the presence of a catalyst like triethylamine. The reaction is carried out at room temperature, and the product is isolated by filtration and recrystallization, yielding a high yield of 90%.

3-Phenyl-1H-pyrazol-5-amine (CAS: 1572-10-7) finds applications in pharmaceuticals, where it serves as a precursor for drug synthesis, and in the semiconductor industry, where it is used as a dopant. It also has potential uses in polymer chemistry and as a ligand in coordination chemistry.

When handling 3-Phenyl-1H-pyrazol-5-amine (CAS: 1572-10-7), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up carefully, and the area should be properly ventilated. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information and emergency procedures.