5-(Methoxycarbonyl)-2-thiophenecarboxylic acid(CAS: 50340-79-9)

5-(Methoxycarbonyl)-2-thiophenecarboxylic acid is a crystalline solid with a molecular weight of approximately 194.23 g/mol. It has a solubility of 2 g/L in water and is sparingly soluble in organic solvents. The compound is moderately reactive, showing limited reactivity with bases and nucleophiles. It does not react with acids and is stable under normal storage conditions.

5-(Methoxycarbonyl)-2-thiophenecarboxylic acid can be synthesized via the condensation of 2-thiophenecarboxylic acid with methanol in the presence of a catalytic amount of a dehydrating agent like phosphorous oxychloride. The reaction is typically carried out under anhydrous conditions to ensure high yields and selectivity.

5-(Methoxycarbonyl)-2-thiophenecarboxylic acid finds applications in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for the development of functional polymers. It is also used in the production of sensors and semiconductors due to its unique chemical properties.

When handling 5-(Methoxycarbonyl)-2-thiophenecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound away from heat and light in a cool, dry place. In case of a spill, use a fume hood and follow proper disposal procedures as indicated in the Safety Data Sheet (SDS).