Bevantolol HCl(CAS: 42864-78-8)

Bevantolol HCl is a white to off-white crystalline powder with a molecular weight of approximately 396.84 g/mol. It is slightly soluble in water and sparingly soluble in ethanol. Bevantolol HCl is relatively stable under normal conditions but can react with acids to form hydrochloric acid. It is used as a prodrug for the β-adrenergic receptor antagonist bevantolol.

Bevantolol HCl is synthesized by reacting bevantolol with hydrochloric acid. The reaction involves the formation of a salt, where the hydrochloride ion is attached to the bevantolol molecule. Commonly, this process is conducted in a solvent such as methanol or ethanol under mild conditions, followed by the removal of solvent to obtain the crystalline product.

Bevantolol HCl is primarily used in the pharmaceutical industry as an intermediate for the preparation of bevantolol, a cardioselective β-adrenergic receptor antagonist used in the treatment of hypertension and angina pectoris. It is not commonly used in other industries such as polymers, sensors, or semiconductors.

When handling Bevantolol HCl, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Bevantolol HCl should be handled in a well-ventilated area or fume hood to prevent inhalation of dust. In case of spillage, it should be cleaned up with caution using appropriate spill control equipment. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.