1-(2-ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole(CAS: 110963-63-8)

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole is a crystalline solid with a molecular weight of approximately 336.41 g/mol. It has limited solubility in water and good solubility in organic solvents like ethanol and dichloromethane. This compound is moderately reactive towards acids and bases. It decomposes above 150°C.

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole can be synthesized via a multi-step process involving the reaction of 2-ethoxyethyl bromide with piperidin-4-ylamine followed by coupling with benzimidazole. Commonly used catalysts include triphenylphosphine and dicyclohexylcarbodiimide. The overall yield is around 50%.

This compound finds applications in the pharmaceutical industry as an intermediate for drug synthesis. It is also used in the development of sensors and as a precursor in the synthesis of certain semiconductors. Its use in polymer chemistry is limited due to its specific reactivity profiles.

When handling 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Use a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed safety information.