5-Acetyl-2,3-dihydrobenzo[b]furan(CAS: 90843-31-5)

5-Acetyl-2,3-dihydrobenzo[b]furan is a crystalline solid with a molecular weight of approximately 172.23 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. The compound is known for its good reactivity towards nucleophiles and electrophiles, making it useful in various organic reactions.

5-Acetyl-2,3-dihydrobenzo[b]furan can be synthesized via a multi-step process involving acetylation of 2,3-dihydrobenzo[b]furan. Commonly, this involves the use of acetyl chloride and a catalyst like anhydrous aluminum chloride in an organic solvent. The yield is typically around 75-80%, and the reaction is carried out under anhydrous conditions.

5-Acetyl-2,3-dihydrobenzo[b]furan is used in pharmaceuticals for the synthesis of certain drug intermediates and in the chemical industry for the production of polymers and sensors. It also finds applications in the development of new materials and semiconductors.

When handling 5-Acetyl-2,3-dihydrobenzo[b]furan, it is important to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, immediately clean up using appropriate absorbents and consult the safety data sheet (SDS) for further instructions.