5-Amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid(CAS: 887256-40-8)

5-Amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid is a crystalline compound with a molecular weight of approximately 440.08 g/mol. It has a high solubility in water and moderate solubility in organic solvents. The compound shows good reactivity with various functional groups and exhibits acidity due to the carboxylic acid moiety.

5-Amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid is typically synthesized through a multistep process involving biphenol sulfation, amidation, and carboxylation reactions. Commonly, the sulfation step is catalyzed by sulfuric acid, followed by protection of the phenolic hydroxyl group and subsequent amidation with an appropriate amine. Finally, the sulfonated biphenyl is converted to the carboxylic acid derivative.

5-Amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid finds applications in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients, in polymer science for functionalizing polymers, in sensor technology for detecting specific analytes, and in semiconductor manufacturing as a dopant material.

When handling 5-Amino-2-hydroxy-4'-sulfo-[1,1'-biphenyl]-3-carboxylic acid, it is essential to wear appropriate personal protective equipment including gloves, goggles, and a lab coat. This compound should be stored in a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbent materials and ensure proper disposal in accordance with local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.