4-(4-Methoxyphenyl)-1-butanol(CAS: 52244-70-9)

4-(4-Methoxyphenyl)-1-butanol (CAS: 52244-70-9) is a colorless liquid with a molecular weight of 190.23 g/mol. It has a high boiling point of 227°C and a low water solubility. This compound is less reactive but can undergo electrophilic substitution reactions. It is widely used in pharmaceuticals and cosmetics due to its chemical stability and functional groups.

4-(4-Methoxyphenyl)-1-butanol (CAS: 52244-70-9) is commonly synthesized via a Friedel-Crafts alkylation reaction using 4-methoxyphenyl magnesium bromide and 1-bromobutane. This method provides a high yield of the desired product with good regioselectivity. The reaction is typically performed under anhydrous conditions to avoid side reactions.

4-(4-Methoxyphenyl)-1-butanol (CAS: 52244-70-9) is utilized in multiple industries, including pharmaceuticals, cosmetics, and agrochemicals. In pharmaceuticals, it serves as a precursor to various drug molecules. In cosmetics, it is used as a skin care ingredient due to its moisturizing properties. Its use in agrochemicals is also noted for its role in developing plant growth regulators.

When handling 4-(4-Methoxyphenyl)-1-butanol (CAS: 52244-70-9), it is essential to wear proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and follow local safety protocols. Always refer to the safety data sheet (SDS) for comprehensive handling guidelines.