methyl 4-hydroxyoxane-4-carboxylate(CAS: 115996-72-0)

Methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0) is a white crystalline solid with a molecular weight of approximately 168.17 g/mol. It is soluble in polar solvents such as water and ethanol. This compound is known for its acidity and undergoes reactions such as esterification and nucleophilic substitution. It has a pKa of around 4.3, indicating moderate acidity.

Methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0) is typically synthesized through the condensation of methyl 4-chloroxane-1,2-dicarboxylate with sodium hydride in a solvent such as dimethylformamide (DMF). The reaction involves the displacement of the chlorine atom with a hydroxyl group, yielding the desired product in good yield. This synthesis is conducted under anhydrous conditions to prevent side reactions.

Methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of other compounds. It is also utilized in the production of polymers for coatings and adhesives. Additionally, this compound finds applications in the development of sensors and semiconductors due to its chemical reactivity and electronic properties.

When handling methyl 4-hydroxyoxane-4-carboxylate (CAS: 115996-72-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using absorbent material and disposed of according to local regulations. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.