Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate(CAS: 38099-82-0)

Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate, or Na(PH2O6), is a crystalline compound with a molecular weight of approximately 228.25 g/mol. It has a high solubility in water and a low reactivity under normal conditions. It is stable in air and light but can degrade under basic conditions. This compound shows good stability in acidic environments and is resistant to hydrolysis at temperatures below 100°C.

Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate is typically synthesized by reacting 6-phosphogluconic acid with sodium hydroxide. The reaction involves the conversion of 6-phosphogluconic acid to its sodium salt, followed by the introduction of a phosphonate group via a phosphonate esterification step. The product is then purified through column chromatography or crystallization for further use.

Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate is used in the pharmaceutical industry, particularly in the development of certain drugs and as a component in some medical formulations. It is also utilized in the polymer industry as a stabilizer or additive, and in the sensor and semiconductor industries for specific functional applications.

When handling Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a well-ventilated area, preferably in a fume hood, to avoid inhalation. Spills should be cleaned up with caution, using appropriate absorbent materials, and the area should be thoroughly washed down with water. Always refer to the Safety Data Sheet (SDS) for specific handling and storage guidelines.