Compound Q&A
How is Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate (CAS: 38099-82-0) typically synthesized?
Answer
Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate is typically synthesized by reacting 6-phosphogluconic acid with sodium hydroxide. The reaction involves the conversion of 6-phosphogluconic acid to its sodium salt, followed by the introduction of a phosphonate group via a phosphonate esterification step. The product is then purified through column chromatography or crystallization for further use.
About
CAS No
38099-82-0
English Name
Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate
Molecular Formula
C6H11Na3O12P2
Molecular Weight
406.06 g/mol
SMILES
C(C(C(C(C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChIKey
CEHGLSKJDFICTB-PWVOXRODSA-K
Last Updated: 2025-09-09 08:06
