cis-4-Aminocyclohexanol(CAS: 40525-78-8)

cis-4-Aminocyclohexanol (CAS: 40525-78-8) is a colorless liquid with a molecular weight of 111.16 g/mol. It has a pKa of 10.4 and a boiling point of 203°C. The compound is slightly soluble in water but miscible with ethanol and acetone. It reacts with acids to form N-acyl derivatives and with aldehydes to form hemiacetals. This chemical is used in the synthesis of pharmaceuticals and fragrances.

cis-4-Aminocyclohexanol is commonly synthesized by reducing 1,4-cyclohexanedione with sodium borohydride in the presence of a suitable solvent. The process is carried out under mild conditions to achieve high yield and selectivity. This method is preferred due to its simplicity and the ease of purification of the product.

cis-4-Aminocyclohexanol (CAS: 40525-78-8) is widely used in the pharmaceutical industry for the synthesis of antifungal drugs. It is also utilized in the fragrance industry to produce perfumes and cosmetics. Additionally, it finds applications in the production of resins and plasticizers for coatings and adhesives.

When handling cis-4-Aminocyclohexanol (CAS: 40525-78-8), ensure proper ventilation and work in a fume hood to minimize inhalation risks. Wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from heat sources and incompatible materials. In case of spill, neutralize with a base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information.