Methyl 5-chloro-2-hydroxybenzoate(CAS: 4068-78-4)

Methyl 5-chloro-2-hydroxybenzoate is a crystalline compound with a molecular weight of approximately 210.59 g/mol. It has a solubility of about 0.6 g/L in water and is slightly soluble in ethanol. This compound exhibits moderate reactivity towards nucleophiles and electrophiles. It is stable under normal conditions but should be protected from moisture and heat.

Methyl 5-chloro-2-hydroxybenzoate is commonly synthesized via the esterification of 5-chloro-2-hydroxybenzoic acid with methanol. The reaction is typically catalyzed by an acid like sulfuric acid and proceeds under mild conditions to give a high yield of around 90%. Selectivity and purity can be enhanced by employing appropriate purification techniques.

Methyl 5-chloro-2-hydroxybenzoate is used in various industries, including pharmaceuticals for the synthesis of certain drugs, and in the production of polymers for their functional properties. It is also utilized in the development of sensors and as a chemical intermediate in semiconductor manufacturing processes.

When handling Methyl 5-chloro-2-hydroxybenzoate, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from heat and moisture. In case of a spill, it should be cleaned up with appropriate safety measures, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.