2-(Adamantan-1-yl)-4-bromophenol(CAS: 104224-68-2)

2-(Adamantan-1-yl)-4-bromophenol (CAS: 104224-68-2) is a crystalline solid with a molecular weight of approximately 302.2 g/mol. It has a low solubility in water and is soluble in organic solvents such as ethanol and chloroform. This compound is known for its limited reactivity, showing basic properties due to the phenolic hydroxyl group and limited reactivity due to the bromine substituent.

2-(Adamantan-1-yl)-4-bromophenol can be synthesized through a multi-step process. Typically, bromination of 4-hydroxyphenyl adamantane using N-bromosuccinimide (NBS) in an organic solvent like dichloromethane is employed. This reaction requires UV light or heat for activation, followed by purification through recrystallization or column chromatography to obtain the desired product.

2-(Adamantan-1-yl)-4-bromophenol (CAS: 104224-68-2) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has applications in the polymer industry as a monomer for specialized polymers. Additionally, it is used in the development of chemical sensors due to its unique reactivity and stability.

When handling 2-(Adamantan-1-yl)-4-bromophenol (CAS: 104224-68-2), proper personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and other reactive materials. In the event of a spill, it should be handled with care using appropriate spill kits. Always consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.