5-Chloro-6-methoxy-2-pyridinamine(CAS: 742070-74-2)

5-Chloro-6-methoxy-2-pyridinamine is a crystalline solid with a molecular weight of approximately 204.64 g/mol. It has a solubility of about 100 mg/L in water and exhibits low reactivity under normal conditions. It is slightly soluble in common organic solvents like ethanol and acetone.

5-Chloro-6-methoxy-2-pyridinamine can be synthesized via the condensation of 4-chloro-2-pyridone with methanol in the presence of an acid catalyst such as hydrochloric acid. The reaction typically yields a mixture, with purification by recrystallization leading to a high-purity product.

5-Chloro-6-methoxy-2-pyridinamine is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in the production of certain polymers and as a component in sensors and semiconductors.

When handling 5-Chloro-6-methoxy-2-pyridinamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled using appropriate spill response materials and procedures. Always consult the Material Safety Data Sheet (MSDS/SDS) for detailed safety information.