2-Bromo-1H-indene-1,3(2H)-dione(CAS: 7319-63-3)

2-Bromo-1H-indene-1,3(2H)-dione (CAS: 7319-63-3) is a crystalline solid with a molecular weight of approximately 226.03 g/mol. It has a melting point of around 125-127°C and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong nucleophiles under certain conditions. It is a key intermediate in the synthesis of various pharmaceuticals and polymers.

2-Bromo-1H-indene-1,3(2H)-dione can be synthesized via the bromination of indene followed by dimerization. Commonly, the bromination is performed using bromine in the presence of a Lewis acid like aluminum bromide. This process requires careful control of reaction conditions to achieve high yield and selectivity. Further steps involve dimerization to form the dione structure.

2-Bromo-1H-indene-1,3(2H)-dione (CAS: 7319-63-3) is primarily used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of various medicinal compounds and functional polymers. Additionally, it can be used in the manufacturing of sensors and semiconductors, although on a smaller scale compared to its pharmaceutical and polymer applications.

When handling 2-Bromo-1H-indene-1,3(2H)-dione (CAS: 7319-63-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.