5-(1H-Pyrrol-1-yl)-1,3-dihydro-2H-benzimidazole-2-thione(CAS: 172152-53-3)

5-(1H-Pyrrol-1-yl)-1,3-dihydro-2H-benzimidazole-2-thione is a white crystalline solid with a molecular weight of approximately 275.3 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Chemically, it is stable but reacts with strong acids and bases. It has a moderate reactivity towards nucleophiles and electrophiles.

5-(1H-Pyrrol-1-yl)-1,3-dihydro-2H-benzimidazole-2-thione is often synthesized via condensation reactions involving pyrrole and benzimidazole derivatives. The process typically requires strong bases and involves multi-step organic synthesis techniques. The yield can range from 60% to 80% depending on the reaction conditions and purity of starting materials.

5-(1H-Pyrrol-1-yl)-1,3-dihydro-2H-benzimidazole-2-thione is used in pharmaceuticals for its antifungal and antimicrobial properties, as well as in the development of sensors and semiconductors due to its unique electronic properties.

When handling 5-(1H-Pyrrol-1-yl)-1,3-dihydro-2H-benzimidazole-2-thione, use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbent materials. Follow standard laboratory safety procedures and keep a safety data sheet (SDS) accessible.