[1,3]Oxazolo[4,5-b]pyridin-2(3H)-one(CAS: 60832-72-6)

1,3-Oxazolo[4,5-b]pyridin-2(3H)-one (CAS: 60832-72-6) is a crystalline solid with a molecular weight of approximately 172.16 g/mol. It has a solubility of 25 mg/L in water. The compound is known for its moderate reactivity, particularly with nucleophiles, and it shows good stability under normal conditions.

1,3-Oxazolo[4,5-b]pyridin-2(3H)-one (CAS: 60832-72-6) is commonly synthesized via a multi-step process involving the reaction of 2-pyridone with 1,3-dioxolane in the presence of an acid catalyst. The yield is typically around 70-80%, and the reaction is exothermic, requiring careful temperature control.

1,3-Oxazolo[4,5-b]pyridin-2(3H)-one (CAS: 60832-72-6) is used in pharmaceuticals for its potential as a precursor in medicinal chemistry, and in the chemical industry for its reactivity in various synthetic pathways. It is also explored in sensor technology and as a component in some polymer formulations.

When handling 1,3-Oxazolo[4,5-b]pyridin-2(3H)-one (CAS: 60832-72-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its moderate reactivity. Spills should be cleaned up immediately using appropriate safety protocols, and a Material Safety Data Sheet (MSDS) should be consulted for detailed safety information.